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The technology of microwave-induced thermo-acoustic tomography that transmits electromagnetic wave pulses to the object and makes it absorb energy, can cause a rapid temperature rise in it. At the same time, a pressure wave will be generated instantaneouly, corresponding to generating an ultrasonic signal which can be detected by an ultrasonic sensor. After the ultrasonic signal is sampled and an image reconstructed, the image can reflect the characteristics of the electromagnetic energy absorbed by the object. The method combines a microwave imaging of high contrast and high resolution ultrasound imaging characteristics, hence verifies theoretically the feasibility of the thermo-acoustic imaging techniques for early breast cancer detection. In this study, we use S-band microwave pulse radiation source to radiate the biological tissue, and also make use of the circling mechanical motion systems to scan the tissue. In order to verify the imaging performance of the simulation experiments, we use both tumors, body and actual biological tissue as the samples of the experiments. The imaging reconstruction and comparative analysis can verify that the experimental system detects and distinguishes the tumor phantoms and the real biological tissue effectively. Results of the performance of high-resolution images and high contrast by the methods can provide further theoretical support for early detecting of breast cancer.
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Keywords:
- early stage detection of breast cancer /
- microwave induced thermo-acoustic tomography /
- image reconstruction /
- ultrasound propagation
[1] Jian X H, Cui Y Y, Xiang Y J, Han Z L 2012 Acta Phys. Sin. 61 217801 (in Chinese) [简小华, 崔崤峣, 向永嘉, 韩志乐 2012 61 217801]
[2] Jiao Y, Jian X H, Xiang Y J, Cui Y Y 2013 Acta Phys. Sin. 62 087803 (in Chinese) [焦阳, 简小华, 向永嘉, 崔崤峣 2013 62 087803]
[3] Huang L, Liu Li X, Lu K, Zhong X C, Li T T, Chen B Z, Rong J, Jiang H B 2013 Journal of Southwest Jiaotong University. 48 264 (in Chinese) [黄林, 刘立新, 鲁奎, 钟小春, 李婷婷, 陈炳章, 荣健, 蒋华北 2013 西南交通大学学报 48 264]
[4] Lou C, Yang S, Ji Z 2012 Physical review letters. 109 218101
[5] Xu M, Wang L V 2003 Physical Review E. 67 056605
[6] Liu G d, Zhang Y R 2011 Acta Phys. Sin. 60 074303 (in Chinese) [刘广东, 张业荣 2011 60 074303]
[7] Ciocan, H Jiang 2004 Med Phys. 31 3231
[8] Yao L, Guo G F, Jiang Huabei 2010 Med Phys. 37 375
[9] Nie L, Xing D, Zhou Q 2008 Medical Physics. 35 4026
[10] Nie L, Ou Z, Yang S 2010 Medical physics. 37 4193
[11] Zhen Yuan, Huabei Jiang 2006 Applied physics letters. 88 231101
[12] Yao Xie, Bin Guo, Geng Ku, Lihong Wang 2008 IEEE Trans On Biomedical Engineering. 55 2741
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[1] Jian X H, Cui Y Y, Xiang Y J, Han Z L 2012 Acta Phys. Sin. 61 217801 (in Chinese) [简小华, 崔崤峣, 向永嘉, 韩志乐 2012 61 217801]
[2] Jiao Y, Jian X H, Xiang Y J, Cui Y Y 2013 Acta Phys. Sin. 62 087803 (in Chinese) [焦阳, 简小华, 向永嘉, 崔崤峣 2013 62 087803]
[3] Huang L, Liu Li X, Lu K, Zhong X C, Li T T, Chen B Z, Rong J, Jiang H B 2013 Journal of Southwest Jiaotong University. 48 264 (in Chinese) [黄林, 刘立新, 鲁奎, 钟小春, 李婷婷, 陈炳章, 荣健, 蒋华北 2013 西南交通大学学报 48 264]
[4] Lou C, Yang S, Ji Z 2012 Physical review letters. 109 218101
[5] Xu M, Wang L V 2003 Physical Review E. 67 056605
[6] Liu G d, Zhang Y R 2011 Acta Phys. Sin. 60 074303 (in Chinese) [刘广东, 张业荣 2011 60 074303]
[7] Ciocan, H Jiang 2004 Med Phys. 31 3231
[8] Yao L, Guo G F, Jiang Huabei 2010 Med Phys. 37 375
[9] Nie L, Xing D, Zhou Q 2008 Medical Physics. 35 4026
[10] Nie L, Ou Z, Yang S 2010 Medical physics. 37 4193
[11] Zhen Yuan, Huabei Jiang 2006 Applied physics letters. 88 231101
[12] Yao Xie, Bin Guo, Geng Ku, Lihong Wang 2008 IEEE Trans On Biomedical Engineering. 55 2741
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