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正电子发射断层扫描(positron emission computed tomography, PET)是核医学领域最先进的临床检查影像技术. PET技术是目前临床上用于诊断和指导治疗肿瘤的最佳手段之一. 正电子发射断层成像设备探测器采集到的数据需要进行数据处理, 把原始数据转换成正弦图形式的数据才能用于图像重建. 平行束断层重建和扇形束图像重建是图像重建的两种方法, 分别对应平行束和扇形束形式的数据处理方法. 对原始数据的操作不可避免地破坏了原始数据的完整性. 现今, 正电子发射断层设备在重建过程中普遍采用平行束重建的方法. 平行束的数据分离会对PET数据进行插值操作, 扇形束的数据分离不会对PET数据进行插值操作. 本文通过对比平行束图像重建和扇形束图像重建结果, 研究了数据插值对PET图像重建结果的影响.
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关键词:
- 正电子发射计算机断层扫描 /
- 数据插值 /
- 图像重建 /
- 原始数据
Positron emission tomography (PET) is the most state-of-the-art clinical examination method in the field of nuclear medicine imaging technology. The PET is one of the best tools for tumor diagnosis and guidance in the clinical treatment. The source data that are obtained by PET, need to be processed into a sinogram form data which can be used for image reconstruction. Parallel beam tomographic reconstruction and fan-beam tomographic reconstruction are two methods of imagetomographic reconstruction, respectively, corresponding to parallel beam data processing and fan beam data processing. The processing of the original data is inevitable to destruct the integrity of original data. Nowadays, the PET is a commonly used method of parallel beam image reconstruction. Parallel beam data processing will change original data by data interpolation operation, and the fan beam data processing avoids data interpolation operation. In this paper, we study the influence of data interpolation on PET image reconstruction by comparing the results obtained by the parallel-beam image reconstruction with those obtained by fan-beam image reconstruction.-
Keywords:
- positron emission tomography /
- interpolation /
- image reconstruction /
- original data
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[2] Tolmachev V, Stone-Elander S 2010 Biochim. Biophys. Acta 1800 487
[3] Reddy S, Robinson M K 2010 Semin. Nucl. Med. 40 182
[4] Ollinger J M, Fessle J A 1997 IEEE Signal Process. Mag. 14 43
[5] Verel I, Visser G W, van Dongen G A 2005 J. Nucl. Med. 46 (Suppl. 1) 164S
[6] Zeng G S 2009 Introduction to Getting Started with Medical Image Reconstruction (Beijing: Higher Education Press) p53 (in Chinese) [曾更生 2009 医学图像重建入门 (北京: 高等教育出版社) 第53页]
[7] Gao F, RyokoY, Mitsuo W, Liu H F 2009 Acta Phys. Sin. 58 3584 (in Chinese) [高飞, 山田亮子, 渡边光男, 刘华锋 2009 58 3584]
[8] Goertzen A L, Bao Q, Bergeron M, Blankemeyer E, Blinder S, Cañadas M, Chatziioannou A F, Dinelle K, Elhami E, Jans H S, Lage E, Lecomte R, Sossi V, Surti S, Tai Y C, Vaquero J J, Vicente E, Williams D A, Laforest R 2012 J. Nucl. Med. 53 1300
[9] Cherry S R, Gambhir S S 2001 ILAR Journal 42 219
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[1] Liu L, Wang Y F 2006 Stereology and Image Analysis Ningbo, October 1, 2006 p147 (in Chinese) [刘力, 王燕芳 2006 中国体视学与图像分析 宁波, 2006年10月1日, p147]
[2] Tolmachev V, Stone-Elander S 2010 Biochim. Biophys. Acta 1800 487
[3] Reddy S, Robinson M K 2010 Semin. Nucl. Med. 40 182
[4] Ollinger J M, Fessle J A 1997 IEEE Signal Process. Mag. 14 43
[5] Verel I, Visser G W, van Dongen G A 2005 J. Nucl. Med. 46 (Suppl. 1) 164S
[6] Zeng G S 2009 Introduction to Getting Started with Medical Image Reconstruction (Beijing: Higher Education Press) p53 (in Chinese) [曾更生 2009 医学图像重建入门 (北京: 高等教育出版社) 第53页]
[7] Gao F, RyokoY, Mitsuo W, Liu H F 2009 Acta Phys. Sin. 58 3584 (in Chinese) [高飞, 山田亮子, 渡边光男, 刘华锋 2009 58 3584]
[8] Goertzen A L, Bao Q, Bergeron M, Blankemeyer E, Blinder S, Cañadas M, Chatziioannou A F, Dinelle K, Elhami E, Jans H S, Lage E, Lecomte R, Sossi V, Surti S, Tai Y C, Vaquero J J, Vicente E, Williams D A, Laforest R 2012 J. Nucl. Med. 53 1300
[9] Cherry S R, Gambhir S S 2001 ILAR Journal 42 219
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