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提出了三维微波热声成像技术检测早期乳腺肿瘤,成像同时具有高对比度和高分辨率的特点.该技术利用自适应的鲁棒Capon波束成形(RCB)算法进行信号处理和图像重建.基于电磁学和声学时域有限差分(FDTD)法,进行微波热声成像仿真,算例结果证实了该技术用于诊断早期乳腺肿瘤的可行性.
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关键词:
- 乳腺癌检测 /
- 微波热声成像 /
- 鲁棒的Capon波束成形 /
- 时域有限差分
We propose a three-dimensional (3D) microwave-induced thermo-acoustic imaging technique for early-stage breast cancer detection, which offers a high imaging contrast and high spatial resolution. The robust Capon beam-forming (RCB) algorithm, which is a data-adaptive approach, is considered for signal processing and image formation. The finite-difference time-domain (FDTD) method is applied to electromagnetic simulation as well as acoustic simulation. The feasibility of this technique is demonstrated via a numerical example based on a 3D breast model.-
Keywords:
- breast cancer detection /
- microwave-induced thermo-acoustic imaging /
- robust Capon beam-forming (RCB) /
- finite-difference time-domain (FDTD)
[1] Liu G D, Zhang Y R 2010 Journal of Nanjing University of Posts and Telecommunications 30 64 (in Chinese) [刘广东、张业荣 2010 南京邮电大学学报 30 64]
[2] Xu X H, Li H 2008 Acta Phys. Sin. 57 4623 (in Chinese) [徐晓辉、李 晖 2008 57 4623]
[3] Xiang L Z, Xing D, Guo H, Yang S H 2009 Acta Phys. Sin. 58 4610 (in Chinese) [向良忠、邢 达、郭 华、杨思华 2009 58 4610]
[4] Ma Y W, Xu Y J, Gao F, Zhao H J, Yang F 2009 Acta Photonica Sinica 38 2423 (in Chinese) [马艺闻、徐雅洁、高 峰、赵会娟、杨 芳 2009 光子学报 38 2423]
[5] Zhang Y R, Nie Z P, Ruan Y Z 1997 Acta Elec. Sin. 25 100 (in Chinese) [张业荣、聂在平、阮颖铮 1997 电子学报 25 100]
[6] Zhu G R, Popovic M, Fang Q Q 2009 IEEE Trans. Magn. 45 1654
[7] Winters D W, Veen B D V, Hagness S C 2010 IEEE Trans. Antennas Propag. 58 145
[8] Fang Q Q, Meaney P M, Paulsen K D 2010 IEEE Trans. Antennas Propag. 58 449
[9] Hagness S C, Taflove A, Bridges J E 1998 IEEE Trans. Biomed. Eng. 45 1470
[10] Xie Y, Guo B, Xu L Z, Li J, Stoica P 2006 IEEE Trans. Biomed. Eng. 53 1647
[11] Guo B, Li J, Zmuda H, Sheplak M 2007 IEEE Trans. Biomed. Eng. 54 2000
[12] O'Halloran M, Jones E, Glavin M 2010 IEEE Trans. Biomed. Eng. 57 830
[13] Ge D B, Yan Y B 2005 Finite-Difference Time-Domain Method for Electromagnetic Waves (2nd ed.) (Xi'an: Xidian University Press) p11 (in Chinese) [葛德彪、闫玉波 2005 电磁波时域有限差分法(第二版)(西安:西安电子科技大学出版社)第11页]
[14] Yuan X J, Borup D, Wiskin J W, Berggren M, Eidens R, Johnson S A 1997 IEEE Trans. Ultrason., Ferroelect., Freq. Contr. 44 816
[15] Katsibas T K, Antonopoulos C S 2004 IEEE Trans. Ultrason., Ferroelect., Freq. Contr. 51 964
[16] Li J, Stoica P, Wang Z S 2003 IEEE Trans. Signal Processing 51 1702
[17] Bernardi P, Cavagnaro M, Pisa S, Piuzzi E 2003 IEEE Trans. Biomed. Eng. 50 295
[18] Taflove A, Hagness S C 2005 Computational Electrodynamics: The Finite-Difference Time-Domain Method (3rd ed.) (Norwood: Artech House) p353
[19] Liu G D, Zhang Y R 2010 Acta Phys. Sin. 59 6969 (in Chinese) [刘广东、张业荣 2010 59 6969]
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[1] Liu G D, Zhang Y R 2010 Journal of Nanjing University of Posts and Telecommunications 30 64 (in Chinese) [刘广东、张业荣 2010 南京邮电大学学报 30 64]
[2] Xu X H, Li H 2008 Acta Phys. Sin. 57 4623 (in Chinese) [徐晓辉、李 晖 2008 57 4623]
[3] Xiang L Z, Xing D, Guo H, Yang S H 2009 Acta Phys. Sin. 58 4610 (in Chinese) [向良忠、邢 达、郭 华、杨思华 2009 58 4610]
[4] Ma Y W, Xu Y J, Gao F, Zhao H J, Yang F 2009 Acta Photonica Sinica 38 2423 (in Chinese) [马艺闻、徐雅洁、高 峰、赵会娟、杨 芳 2009 光子学报 38 2423]
[5] Zhang Y R, Nie Z P, Ruan Y Z 1997 Acta Elec. Sin. 25 100 (in Chinese) [张业荣、聂在平、阮颖铮 1997 电子学报 25 100]
[6] Zhu G R, Popovic M, Fang Q Q 2009 IEEE Trans. Magn. 45 1654
[7] Winters D W, Veen B D V, Hagness S C 2010 IEEE Trans. Antennas Propag. 58 145
[8] Fang Q Q, Meaney P M, Paulsen K D 2010 IEEE Trans. Antennas Propag. 58 449
[9] Hagness S C, Taflove A, Bridges J E 1998 IEEE Trans. Biomed. Eng. 45 1470
[10] Xie Y, Guo B, Xu L Z, Li J, Stoica P 2006 IEEE Trans. Biomed. Eng. 53 1647
[11] Guo B, Li J, Zmuda H, Sheplak M 2007 IEEE Trans. Biomed. Eng. 54 2000
[12] O'Halloran M, Jones E, Glavin M 2010 IEEE Trans. Biomed. Eng. 57 830
[13] Ge D B, Yan Y B 2005 Finite-Difference Time-Domain Method for Electromagnetic Waves (2nd ed.) (Xi'an: Xidian University Press) p11 (in Chinese) [葛德彪、闫玉波 2005 电磁波时域有限差分法(第二版)(西安:西安电子科技大学出版社)第11页]
[14] Yuan X J, Borup D, Wiskin J W, Berggren M, Eidens R, Johnson S A 1997 IEEE Trans. Ultrason., Ferroelect., Freq. Contr. 44 816
[15] Katsibas T K, Antonopoulos C S 2004 IEEE Trans. Ultrason., Ferroelect., Freq. Contr. 51 964
[16] Li J, Stoica P, Wang Z S 2003 IEEE Trans. Signal Processing 51 1702
[17] Bernardi P, Cavagnaro M, Pisa S, Piuzzi E 2003 IEEE Trans. Biomed. Eng. 50 295
[18] Taflove A, Hagness S C 2005 Computational Electrodynamics: The Finite-Difference Time-Domain Method (3rd ed.) (Norwood: Artech House) p353
[19] Liu G D, Zhang Y R 2010 Acta Phys. Sin. 59 6969 (in Chinese) [刘广东、张业荣 2010 59 6969]
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