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Time irreversibility of electric cardiac graph(ECG) signal can reflect the physiological function and the health condition of the heart. In this paper,we propos a symbolic relative entropy method (first symbolizing and then determining the time irreversibility) to analyze the three kinds of ECG signals, i.e., normal sinus rhythm, ventricular fibrillation and sudden cardiac death from the MIT-BIH database. The results show that three kinds of signals have different time irreversibilityies, and the time irreversibility range is largest for the normal sinus rhythm, the second largest for the ventricular fibrillation, and smallest for the sudden cardiac death. Variance test results indicate that the irreversibilities of the three signals are significantly different. The results show that the relative entropy method can play a positive role in heart disease detection and diagnosis.
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Keywords:
- ECG signal /
- relative entropy /
- time irreversibility
[1] Josephson M E,Callans D J,Buxton A E 2000 Ann.Intern Med. 133 901
[2] Bian C H,Ning X B 2004 Chin. Phys. 13 633
[3] Ning X B,Bian C H,Wang J,Chen Y 2006 Chin. Sci.Bull. 51 385
[4] Costa M,Goldberger A L,Peng C K 2005 Phys. Rev. Lett. 95 198102
[5] Porta A,Guzzetti S,Montano N,Gnecchi-Ruscone T,Furlan R,Malliani A 2006 Computers in Cardiol. 33 77
[6] Camillo C, Enrico R 2007 Chaos 32 1649
[7] Costa M,Peng C K,Goldberger A L 2008 Cardiovasc Eng. 8 88
[8] Daw C S, Finney C E A 2003 Rev. Sci. Instrum 74 915
[9] Guzzetti S, Borroni E, Garbelli P E, Ceriani E,Bella P D,Montano N,Cogliati C,Somers V K,Mallani A,Porta A 2005 Circulation 112 465
[10] Thomas M C, Joy A T(Translated by Ruan G S,Zhang H)2007 Information Theory (Beijing: Machine Press) pp13-14 (in Chinese)
[11] Porporato A,Rigby J R,Daly E 2007 Phys. Rev. Lett.98 094101
[12] Wessel N, Ziehmann C, Kurths J,Meyerfeldt U,Schirdewan A,Voss A 2000 Phys. Rev. E 61 733
[13] Parlitz U,Berg S,Luther S,Schirdewan A,Kurths J,Wessel N 2010 Proceedings of the Sixth ESGCO, Berlin, Germany, April 12-14,2010 30 p1
[14] Ma B R,Chen H 2005 Statistical Methods in Medical Research (Beijing:Science Press )p44 (in Chinese)[马斌荣、陈 卉 2005 医学科研中的统计方法 (北京:科学出版社)第44页]
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[1] Josephson M E,Callans D J,Buxton A E 2000 Ann.Intern Med. 133 901
[2] Bian C H,Ning X B 2004 Chin. Phys. 13 633
[3] Ning X B,Bian C H,Wang J,Chen Y 2006 Chin. Sci.Bull. 51 385
[4] Costa M,Goldberger A L,Peng C K 2005 Phys. Rev. Lett. 95 198102
[5] Porta A,Guzzetti S,Montano N,Gnecchi-Ruscone T,Furlan R,Malliani A 2006 Computers in Cardiol. 33 77
[6] Camillo C, Enrico R 2007 Chaos 32 1649
[7] Costa M,Peng C K,Goldberger A L 2008 Cardiovasc Eng. 8 88
[8] Daw C S, Finney C E A 2003 Rev. Sci. Instrum 74 915
[9] Guzzetti S, Borroni E, Garbelli P E, Ceriani E,Bella P D,Montano N,Cogliati C,Somers V K,Mallani A,Porta A 2005 Circulation 112 465
[10] Thomas M C, Joy A T(Translated by Ruan G S,Zhang H)2007 Information Theory (Beijing: Machine Press) pp13-14 (in Chinese)
[11] Porporato A,Rigby J R,Daly E 2007 Phys. Rev. Lett.98 094101
[12] Wessel N, Ziehmann C, Kurths J,Meyerfeldt U,Schirdewan A,Voss A 2000 Phys. Rev. E 61 733
[13] Parlitz U,Berg S,Luther S,Schirdewan A,Kurths J,Wessel N 2010 Proceedings of the Sixth ESGCO, Berlin, Germany, April 12-14,2010 30 p1
[14] Ma B R,Chen H 2005 Statistical Methods in Medical Research (Beijing:Science Press )p44 (in Chinese)[马斌荣、陈 卉 2005 医学科研中的统计方法 (北京:科学出版社)第44页]
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