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A method of fast scanning X-ray microprobe fluorescence imaging, on-the-fly scan, has been recently accomplished in BL15U1 hard X-ray micro-focus beamline of Shanghai Synchrotron Radiation Facility, based on the software platform of EPICS; the high technology of precise motion control, the X-ray flux detection and the X-ray fluorescence spectrum detection are integrated into this system. By the method of X-ray microprobe fluorescence imaging, the images of standard nickel mask and the elemental distribution of copper, zinc, kalium and iron in specimen of mouse spleen are obtained. The results demonstrate that this method not only enhances the efficiency on a large scale, but also achieves high quality fluorescence mapping.
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Keywords:
- fast scanning X-ray microprobe fluorescence imaging /
- synchrotron radiation /
- trace elemental distribution
[1] Xu Y S, Yang X R, Wang H Y, Tang L, Liu C C, Wei X, Tan D Z 2005 Acta Phys. Sin. 54 4 (in Chinese) [徐岳生、杨新荣、王海云、唐 蕾、刘彩池、魏 欣、覃道志 2005 54 4]
[2] Cheng L, Ding X L, Liu Z G, Pan Q L, Chu X L, Feng S L 2007 Acta Phys. Sin. 56 12 (in Chinese) [程 琳、丁训良、刘志国、潘秋丽、初学莲、冯松林 2007 56 12]
[3] Ingram P, Shelburne J, Roggli V, LeFurgey A 1999 Biomedical Applications of Microprobe Analysis (San Diego: Academic Press) pp31— 41
[4] Bearse R C, Close D A, Malanify J J, Umbarger C J 1974 Anal. Chem. 46 4
[5] Bohic S, Simionovici A, Snigirev A, Ortega R, Devès G, Heymann D, Schroer C G 2001 Appl. Phys. Lett. 78 22
[6] Ortega R, Cloetens P, Devès G, Carmona A, Bohic S 2007 PloS ONE 2 9 e925
[7] Kemner K M, Kelly S D, Lai B, Maser J, O’Loughlin E J, Sholto-Douglas D, Cai Z, Schneegurt M A, Kulpa C F, Jr., Nealson K H 2004 Science 306 5696
[8] Yang L, McRae R, Henary M M, Patel R, Lai B, Vogt S, Fahrni C J 2005 PNAS 102 32
[9] Fahrni C J 2007 Current Opinion in Chemical Biology 11 2
[10] Ma L D, Yang F J 2005 The application of synchrotron radiation (Shanghai: Fudan University Press) pp202—215 [马礼敦、杨福家 2005 同步辐射应用概论 (上海:复旦大学出版社) 第202—215页]
[11] Yan F, Li A G, Yang K, Wang H, Yu X H 2009 Nuclear Techniques 32 11 (in Chinese) [闫 芬、李爱国、杨 科、王 华、余笑寒 2009 核技术 32 11]
[12] Ceng L, Cui Y H, Fu X L, Jia S Y 1998 Acta Laboratorium Animalis Scientia Sinica 6 2 (in Chinese) [曾 林、崔海银、付兴伦、贾世玉 1998 中国实验动物学报 6 2]
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[1] Xu Y S, Yang X R, Wang H Y, Tang L, Liu C C, Wei X, Tan D Z 2005 Acta Phys. Sin. 54 4 (in Chinese) [徐岳生、杨新荣、王海云、唐 蕾、刘彩池、魏 欣、覃道志 2005 54 4]
[2] Cheng L, Ding X L, Liu Z G, Pan Q L, Chu X L, Feng S L 2007 Acta Phys. Sin. 56 12 (in Chinese) [程 琳、丁训良、刘志国、潘秋丽、初学莲、冯松林 2007 56 12]
[3] Ingram P, Shelburne J, Roggli V, LeFurgey A 1999 Biomedical Applications of Microprobe Analysis (San Diego: Academic Press) pp31— 41
[4] Bearse R C, Close D A, Malanify J J, Umbarger C J 1974 Anal. Chem. 46 4
[5] Bohic S, Simionovici A, Snigirev A, Ortega R, Devès G, Heymann D, Schroer C G 2001 Appl. Phys. Lett. 78 22
[6] Ortega R, Cloetens P, Devès G, Carmona A, Bohic S 2007 PloS ONE 2 9 e925
[7] Kemner K M, Kelly S D, Lai B, Maser J, O’Loughlin E J, Sholto-Douglas D, Cai Z, Schneegurt M A, Kulpa C F, Jr., Nealson K H 2004 Science 306 5696
[8] Yang L, McRae R, Henary M M, Patel R, Lai B, Vogt S, Fahrni C J 2005 PNAS 102 32
[9] Fahrni C J 2007 Current Opinion in Chemical Biology 11 2
[10] Ma L D, Yang F J 2005 The application of synchrotron radiation (Shanghai: Fudan University Press) pp202—215 [马礼敦、杨福家 2005 同步辐射应用概论 (上海:复旦大学出版社) 第202—215页]
[11] Yan F, Li A G, Yang K, Wang H, Yu X H 2009 Nuclear Techniques 32 11 (in Chinese) [闫 芬、李爱国、杨 科、王 华、余笑寒 2009 核技术 32 11]
[12] Ceng L, Cui Y H, Fu X L, Jia S Y 1998 Acta Laboratorium Animalis Scientia Sinica 6 2 (in Chinese) [曾 林、崔海银、付兴伦、贾世玉 1998 中国实验动物学报 6 2]
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