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Deconvolution methods are not feasible in spectral domain optical coherence tomography (SD-OCT) system due to the linear space variant property of its axial point spread function (PSF). In order to improve the axial resolution and enhance the imaging quality of the SD-OCT system, a Lucy-Richardson algorithm based deconvolution method is implemented with the numerically compensated A-scan signals and the effective axial PSF in this paper. The main factors decreasing the value of PSF along the axial direction and blurring the images, as well as the deconvolution process, are theoretical studied. With the developed SD-OCT system, the axial modulation function of the PSF is retrieved by curve fitting of the measured peak values of the PSF at different axial positions. After compensating the A-scan signal with the modulation function, deconvolution is performed with the measured effective axial PSF. In vivo imaging on typical samples is conducted and reconstruction is done based on the deconvolution method. The comparing results demonstrate that the proposed deconvolution method not only enhances the axial resolution but also improves the depth dependent sensitivity fall-off in SD-OCT system.
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Keywords:
- spectral domain optical coherence tomography /
- Lucy-Richardson deconvolution /
- effective point spread function
[1] ［1］Huang D, Swanson E A, Lin C P, Schuman J S, Stinson W G, Chang W, Hee M R, Flotte T, Gregory K, Puliafito C A, Fujimoto J G 1991 Science 254 1178
[2] ［2］Yu X F, Ding Z H, Chen Y H 2006 Acta Opt. Sin. 26 235 (in Chinese) ［俞晓峰、 丁志华、 陈宇恒 2006光学学报 26 235］
[3] ［3］Liang Y M, Zhou D C, Meng F Y, Wang M W 2007 Acta Phys. Sin. 56 3246 (in Chinese) ［梁艳梅、 周大川、 孟凡勇、 王明伟 2007 56 3246］
[4] ［4］Jia Y Q, Liang Y M, Zhu X N 2007 Acta Phys. Sin. 56 3861 (in Chinese) ［贾亚青、 梁艳梅、 朱晓农 2007 56 3861］
[5] ［5］Yang Y L, Ding Z H, Wang K, Wu L, Wu L 2009 Acta Phys. Sin. 58 1773 (in Chinese) ［杨亚良、 丁志华、 王凯、 吴凌、 吴兰 2009 58 1773］
[6] ［6］Wang K, Ding Z H 2008 Chin. Opt. Lett. 6 902
[7] ［7］Yun S H, Tearney G J, Bouma B E, Park B H, de Boer J F 2003 Opt. Express 11 3598
[8] ［8］Morgner U, Drexler W, Kartner F X, Li X D, Pitris C, Ippen E P, Fujimoto J G 2000 Opt. Lett. 25 111
[9] ［9］Hartl I, Li X D, Chudoba C, Ghanta R K, Ko T H, Fujimoto J G, Ranka J K, Windeler R S 1999 Opt. Lett. 26 608
[10] ］Schmitt J M, Xiang S H, Yung K M 1998 J. Opt. Soc. Am.A 15 2288
[11] ］Sathyam U S, Colston B W, Da Silva L B, Everett M J 1999 Appl. Opt. 38 2097
[12] ］Xiang J Y, Wu Z, Zeng S Q, Luo Q M, Zhang P, Huang D X 1999 Acta Phys. Sin. 48 1831 (in Chinese) ［向际鹰、 吴震、 曾邵群、 骆清铭、 张平、 黄德修 1999 48 1831］
[13] ］Liu Y H, Liang Y M, Mu G G, Zhu X N 2009 J. Opt. Soc. Am. A 26 72
[14] ］Paesl S, Ruy S Y, Choi J N E, Lee B H, Hong I K 2005 Opt. Quant. Electron. 37 1225
[15] ］Bajraszewski T, Wojtkowski M, Szkulmowski M, Szkulmowska A, Huber R 2003 Opt. Express 16 4163
[16] ］Ralston T S, Marks D L, Kamalabadi F, Boppart S A 2005 IEEE Trans. Image Process 14 1254
[17] ］Hu Z L, Pan Y S, Rollins A M 2007 Appl. Opt. 46 8499
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[1] ［1］Huang D, Swanson E A, Lin C P, Schuman J S, Stinson W G, Chang W, Hee M R, Flotte T, Gregory K, Puliafito C A, Fujimoto J G 1991 Science 254 1178
[2] ［2］Yu X F, Ding Z H, Chen Y H 2006 Acta Opt. Sin. 26 235 (in Chinese) ［俞晓峰、 丁志华、 陈宇恒 2006光学学报 26 235］
[3] ［3］Liang Y M, Zhou D C, Meng F Y, Wang M W 2007 Acta Phys. Sin. 56 3246 (in Chinese) ［梁艳梅、 周大川、 孟凡勇、 王明伟 2007 56 3246］
[4] ［4］Jia Y Q, Liang Y M, Zhu X N 2007 Acta Phys. Sin. 56 3861 (in Chinese) ［贾亚青、 梁艳梅、 朱晓农 2007 56 3861］
[5] ［5］Yang Y L, Ding Z H, Wang K, Wu L, Wu L 2009 Acta Phys. Sin. 58 1773 (in Chinese) ［杨亚良、 丁志华、 王凯、 吴凌、 吴兰 2009 58 1773］
[6] ［6］Wang K, Ding Z H 2008 Chin. Opt. Lett. 6 902
[7] ［7］Yun S H, Tearney G J, Bouma B E, Park B H, de Boer J F 2003 Opt. Express 11 3598
[8] ［8］Morgner U, Drexler W, Kartner F X, Li X D, Pitris C, Ippen E P, Fujimoto J G 2000 Opt. Lett. 25 111
[9] ［9］Hartl I, Li X D, Chudoba C, Ghanta R K, Ko T H, Fujimoto J G, Ranka J K, Windeler R S 1999 Opt. Lett. 26 608
[10] ］Schmitt J M, Xiang S H, Yung K M 1998 J. Opt. Soc. Am.A 15 2288
[11] ］Sathyam U S, Colston B W, Da Silva L B, Everett M J 1999 Appl. Opt. 38 2097
[12] ］Xiang J Y, Wu Z, Zeng S Q, Luo Q M, Zhang P, Huang D X 1999 Acta Phys. Sin. 48 1831 (in Chinese) ［向际鹰、 吴震、 曾邵群、 骆清铭、 张平、 黄德修 1999 48 1831］
[13] ］Liu Y H, Liang Y M, Mu G G, Zhu X N 2009 J. Opt. Soc. Am. A 26 72
[14] ］Paesl S, Ruy S Y, Choi J N E, Lee B H, Hong I K 2005 Opt. Quant. Electron. 37 1225
[15] ］Bajraszewski T, Wojtkowski M, Szkulmowski M, Szkulmowska A, Huber R 2003 Opt. Express 16 4163
[16] ］Ralston T S, Marks D L, Kamalabadi F, Boppart S A 2005 IEEE Trans. Image Process 14 1254
[17] ］Hu Z L, Pan Y S, Rollins A M 2007 Appl. Opt. 46 8499
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