基于复杂度的针刺脑电信号特征提取

边洪瑞; 王江; 韩春晓; 邓斌; 魏熙乐; 车艳秋

doi:10.7498/aps.60.118701

摘要

为探究针灸刺激对大脑活动产生的影响,文章设计了4种针刺频率针刺右腿足三里穴获取脑电的实验.首次采用排序递归图和关联维数方法提取针刺脑电信号的复杂度参数来反映针刺大脑的功能状态,并基于这些方法研究了针刺作用对大脑功能区域的影响以及不同针刺频率与脑电复杂度的相关性.发现针刺时脑电的复杂度高于针刺前,尤以频率为100次/min的针刺影响最为明显;从FP2, F7, T3导联脑电中提取的确定性指标(DET)可作为区分针刺状态与针刺前状态的一种特征参数.

关键词:

针灸 /
脑电 /
排序递归图 /
关联维数

Abstract

To explore the effects of acupuncture stimulation on brain activities, an experiment is designed that acupunctures at Zusanli point of the right leg are performed at four different frequencies to obtain electroencephalograph (EEG) signals. For the first time the complexity parameter of EEG is extracted by order recurrence plot and correlation dimension method, which reflects the functional state of the brain under acupuncture. The effects of acupuncture on the functional region of brain and correlation among different acupuncture frequencies and the complexity of EEG are investigated. The results show that the complexity of EEG during acupuncture is higher than that before acupuncture and especially during acupuncture at a frequency of 100 times/min. Furthermore, the determinism (DET) extracted from EEG signals of electrodes FP2, F7 and T3 can be used as a characteristic parameter of distinction between the state during acupuncture and the state before acupuncture.

Keywords:

作者及机构信息

(1)天津大学电气与自动化工程学院,天津 300072; (2)天津职业技术师范大学,天津 300222

基金项目: 国家自然科学基金重点项目(批准号:50537030)、国家自然科学基金(批准号:61072012)和国家自然科学基金青年科学基金(批准号:50907044,60901035)资助的课题.

Authors and contacts

(1)School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072, China; (2)Tianjin University of Technology and Education, Tianjin 300222, China

参考文献

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施引文献

[1]	Yuan H, Yuan L R, Ma H F, Zhang L 2002 Acupuncture Research 27 211 (in Chinese) [袁红、袁丽荣、马惠芳、张丽 2002 针刺研究 27 211]
[2]	Li W M, Chen Y B, Wang X Y 2008 Acupuncture Research 33 65 (in Chinese) [李为民、陈颖波、王晓艳 2008 针刺研究 33 65]
[3]	Han C X, Wang J, Che Y Q, Deng B, Guo Y, Guo Y M, Liu Y Y 2010 Acta Phys. Sin. 59 5880 (in Chinese) [韩春晓、王江、车艳秋、邓斌、郭义、郭永明、刘阳阳 2010 59 5880]
[4]	Shen J 2001 J. Altern. Complement Med. 7 S121
[5]	Hawkins D R 1995 Power vs. Force: The Hidden Determinants of Human Behavior(Sedona: Veritas Publishing)p83
[6]	Gollub R L, Hui K K S, Stefano G B 1999 Acta Pharmacologica Sinica 20 769
[7]	Cho Z H, Oleson T D, Alimi D, Niemtzow R C 2002 J. Altern. Complement Med. 8 399
[8]	Wu M T, Sheen J M, Chuang K H, Yang P, Chin S L, Tsai C Y, Chen C J, Liao J R, Lai P H, Chu K A, Pan H B, Yang C F 2002 Neuroimage 16 1028
[9]	Zhang W T, Jin Z, Luo F, Zhang L, Zeng Y W, Han J S 2004 Neurosci Lett. 354 50
[10]	Shen H, Wang B J, Tang X W 2006 Chin. J. Med. Phys. 23 216 (in Chinese) [沈花、王宝俊、唐孝威 2006中国医学物理学杂志 23 216]
[11]	Yin L, Jin X L, Shi X, Tian J H, Ma L, Yi D Y, Zeng H N 2002 Chin. J. Rehabilitation Theory and Practice 8 523 (in Chinese) [尹岭、金香兰、石现、田嘉禾、马林、尹大一、曾海宁 2002 中国康复理论与实践 8 523]
[12]	Paraskeva A, Melemeni A, Petropoulos G, Siafaka I, Fassoulaki A 2004 Am. J. Chin. Med. 32 789
[13]	Li L, Jin Z L, Li B 2011 Acta Phys. Sin. 60 048703 (in Chinese) [李凌、金贞兰、李斌 2011 60 048703]
[14]	Ma Q L, Bian C H, Wang J 2010 Acta Phys. Sin. 59 4480 (in Chinese) [马千里、卞春华、王俊 2010 59 4480]
[15]	Meng Q F, Zhou W D, Chen Y H, Peng Y H 2010 Acta Phys. Sin. 59 123 (in Chinese) [孟庆芳、周卫东、陈月辉、彭玉华 2010 59 123]
[16]	Fang X L, Jiang Z L 2007 Acta Phys. Sin. 56 7330 (in Chinese) [方小玲、姜宗来 2007 56 7330]
[17]	Ye M Y, Wang X D, Zhang H R 2005 Acta Phys. Sin. 54 2568 (in Chinese) [叶美盈、汪晓东、张浩然 2005 54 2568]
[18]	Xie Y, Xu J X, Yang H J, Hu S J 2002 Acta Phys. Sin. 51 205 (in Chinese) [谢勇、徐健学、杨红军、胡三觉 2002 51 205]
[19]	Hwa R C, Ferree T C 2002 Phys. Rev. E 66 021901
[20]	He T, Zhou Z O 2007 Acta Phys. Sin. 56 0693 (in Chinese) [贺涛、周正欧 2007 56 0693]
[21]	Stam C J, van Woerkom T C, Pritchard W S 1996 Electroencephalogr Clin Neurophysiol 99 214
[22]	Lee Y J, Zhu Y S, Xu Y H, Shen M F, Zhang H X, Thakor N V 2001 Clin Neurophysiol 112 1288
[23]	Liu H F, Dai Z H, Chen F, Gong X, Yu Z H 2002 Acta Phys. Sin. 51 1186 (in Chinese) [刘海峰、代正华、陈峰、龚欣、于尊宏 2002 51 1186]
[24]	Dong F, Jin N D, Zong Y B, Wang Z Y 2008 Acta Phys. Sin. 57 6145 (in Chinese) [董芳、金宁德、宗艳波、王振亚 2008 57 6145]
[25]	Takens F 1981 Dynamical Systems and Turbulence (Springer Berlin, Heidelberg) p366
[26]	Groth A 2005 Phys. Rev. E 72 046220
[27]	Li C S, Wang H, Zhao H B, Liu C 2009 Chin. J. Biomedical Engineering 28 846 (in Chinese) [李春胜、王宏、赵海滨、刘冲 2009 中国生物医学工程学报 28 846]
[28]	Lopes da Silva F H, Hoek A, Smits H, Zetterberg L H 1974 Kybernetik 15 27
[29]	Wendling F, Bellanger J J, Bartolomei F, Chauvel P 2000 Biol. Cybern 83 367
[30]	Abarbanel H D I, Kennel M B 1993 Phys. Rev. E 47 3057
[31]	Fraser A M, Swinney H L 1986 Phys. Rev. A 33 1134

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