The precise, uniform and constant wireless transmission of electromagnetic power to multiple targets in a local finite space is a scientific problem to be solved urgently. Aiming at this problem, this paper proposes an automatic zone selection channel matching method based on time reversal (TR) technique which has the spatio-temporal focusing characteristics. The proposed method can not only adaptively compensate the channel differences at different targets based on the contribution rate of the multipath signals, but also dynamically divide the working range of the time reversal mirror (TRM) elements to eliminate the mutual influences between different targets through the use of the distance coefficient. While improving the accuracy of energy focusing, the proposed method also solves the problem that non-uniform microwave power transmission (MPT) of multiple targets, and therefore it achieves constant, uniform and long-time MPT of multi-targets.