An experimental study of supercontinuum generation in a photonic crystal fiber with zero dispersion wavelength 780?nm by femtosecond laser and its dependence factor is presented. Supercontinuum light with a spectrum more than one octave broad (500-1100?nm) was generated in a photonic crystalfiber by femtosecond pulses from a selfstarting, selfmode locked Ti:sapphire oscillator running at center wavelength of 810-840?nm. Different supercontinuums were generated by the 35?fs pulses with different power, central wavelength, prechirp, and the continuous noise in the femtosecond pulses. Some reasonable analysis result is obtained from the comparisons of the experimental results, and the mechanism of the supercontinuum generation is analyzed.