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中国物理学会期刊

基于镂空阵列探头的反射式光声/热声双模态组织成像

Reflection mode photoacoustic/thermoacoustic dual modality imaging based on hollow concave array

CSTR: 32037.14.aps.70.20202012
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  • 光声和热声成像技术除激发源不同外, 可共用一套数据采集和处理系统, 具有天然的融合优势. 本文提出了一种基于镂空阵列的反射式光声/热声双模态成像技术, 该技术利用光纤与天线, 通过镂空阵列的开孔进行光声/热声信号激发, 使得激发光、微波和接收超声信号共轴, 构成明场光声/热声双模态成像模式. 通过对探头镂空部分晶元相位和幅值的补偿校准, 成功实现了3 mm直径塑料管、人体手臂、手背和脚背的双模态成像. 实验结果表明: 系统空间分辨率为0.33 mm, 双模态成像技术可同时提供组织的光学和微波吸收分布, 有助于肿瘤、糖尿病足等疾病的精准检测, 具有极广泛的临床应用前景.

     

    Photoacoustic (PA) and thermoacoustic (TA) imaging can share a set of data acquisition and data processing system, in addition to different excitation sources. In this paper, a reflection mode PA/TA dual modality imaging based on a hollow concave array is proposed. The PA/TA signals are excited through the holes in the hollow array by using optical fiber and dipole antenna, respectively. The excited light, microwave and received ultrasonic signals are coaxial, forming a PA/TA dual modality imaging mode. Through the compensation and calibration of the transducer crystal phase and amplitude of the hollow part of the array, a 3-mm-diameter plastic tube filled with 0.9 wt.% salt water, safflower oil, human arm, back of hand and instep are successfully imaged, separately. These experimental results show that the spatial resolution of the PA/TA dual modality imaging system is 0.33 mm, and this technology has a potential to provide the optical and microwave absorption distribution of tissues at the same time by using the same hollow concave array, which is helpful in accurately detecting tumor, diabetic foot and other diseases, and has a wide range of clinical application prospects.

     

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