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中国物理学会期刊

双参数分岔平面内胰腺细胞的簇放电分析

CSTR: 32037.14.aps.60.110202

Study on bursting of pancreatic cells in codimension-2 bifurcation regions

CSTR: 32037.14.aps.60.110202
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  • 胰岛分泌胰岛素的放电活动以动作电位的簇放电为主要特点.文章考虑具有代表性且较为简单的Vries-Sherman模型,通过其快子系统的双参数分岔分析确定了双参数平面内不同簇放电类型的存在区域,并应用快慢动力学分析研究了参数vm取不同值时所产生的簇放电模式的拓扑类型以及它们之间相互转迁的动力学机理.

     

    Electrical activities of insulin secretion in pancreatic islets are characterized by bursts of action potentials. With a simple but representative Vries-Sherman model, we determine the regions of different types of bursting in two-parameter plane through the two-parameter bifurcation analysis of the fast subsystem. Moreover, fast/slow analysis is used to reveal topological types of bursting patterns for different values of the parameter Vm and transition mechanisms between them.

     

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