According to solar cell’s temperature properties and thermoelectric power properties, a refrigerator model is newly designed, which is driven by solar photovoltaic and thermoelectric power generation. It includes solar cells, thermoelectric power modules, power control system, etc. Based on the load demand for electricity, a photovoltaic power generation system is designed. The operating efficiency and exergy efficiency of the model are analyzed by thermodynamic theory. We find that the COP (coefficient of performance) achieves 2.73 (COP is about 2 for general refrigerators) and exergy efficiency achieves 42.5%. By using the model, the emissions of carbon dioxide 1394.2 kg, sulfur dioxide 27.2 kg and nitrogen oxides 21.0 kg are reduced, which can provide an interesting direction to the applications of renewable energy.