The synchronization problem of uncertain dynamical network model with time-delay nodes has been researched, where the network structure is known or totally unknown. Based on Lyapunov stability theorem, the synchronization controller of complex networks and the adaptive controller of synchronization of complex networks are designed respectively under the circumstances of known parameters and unknown parameters. The sufficient condition of network synchronization is given to guarantee that the dynamical network asymptotically synchronizes at the individual node state in arbitrary specified network. Finally, numerical simulations are provided to verify the effectiveness of the developed methods.