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The resolution of adaptive optics confocal scanning laser ophthalmoscope is constrained by human eye’s aberration, numberical aperture and pinhole size. A super resolved adaptive optics confocal scanning laser ophthalmoscope is presented. By using adaptive optics to detect and compensate human eye’s aberration, and using optical superresolution to improve resolution which is degraded by large pinhole size, the system can achieve high resolution, real-time human retina image in vivo .
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Keywords:
- superresolution /
- confocal scanning microscopy /
- ophthalmoscopy /
- adaptive optics
[1] Elsner A E, Zhou Q, Beck F 2000 Opt. Express 7 95
[2] Rawlinson A A , Cucevic V, Nugent K A, Brooks A M V, Klein A G 2000 J. Opt. Soc. Am. 17 477
[3] Fallon T J, Chowiencyzk P, Kohner E M Br 1986 J. Ophthalmol. 70 43
[4] Webb R H, Hughes G W, Delori F C 1987 Apply Optics 26 1492
[5] Liang J, Williams D R, Miller D 1997 J. Opt. Soc. Am. A 14 2884
[6] Roorda A, Romero-Borja F, Donnelly W J, Queener H, Hebert T J, Campbell M C W 2002 Opt. Express 10 405
[7] Zhang Y D, Ling N, Rao X J, Li X Y, Wang W, Ma X A, Jiang W H 2002 Proceeding of the 3rd International Workshop on Adaptive Optics for Industry and Medicine Ed. S. R. Restaino & S. W. Teare 97
[8] Ling N, Zhang Y D, Rao X J, Li X Y, Wang C, Hu Y Y, Jiang W H 2002 Proc. of SPIE 4825 99
[9] Ling N, Zhang Y D, Rao X J, Wang C, Hu Y Y, Jiang W H, Jiang C H 2004 Proc. of SPIE 5639 37
[10] Ling N ,Zhang Y D, Rao X J, Wang C, Hu Y Y, Jiang Y Y 2005 Chinese Optics Letters 3 225
[11] Lu J, Zhang Y D, Rao X J, Shi G H, Yang H S, Wang C 2007 Proc. of SPIE 6624 662420
[12] Lu J, Li H, Wei L, Shi G H, Zhang Y D 2009 Proc. of SPIE 7519 75191l
[13] Shi G H,Dai Y,Wang L,Ding Z H,Rao X J,Zhang Y D 2008 Chinese Optics Letters 6 424
[14] 激光产品的安全.GB 7247.1-2001 idt IEC 60825-1: 1993
[15] Gu M, Tannous T, Sheppard J R 1996 Optics Letters 21 312
[16] Sieracki C K, Hansen E W 1994 Proc. of SPIE 2148 120
[17] Sheppard C J R 1995 Optik 99 32
[18] Deng X Q, Wang G Y, Xu Z Z 2001 Chinese Journal of Lasers 28 459(in Chinese) [邓小强、王桂英、徐至展 2001 中国激光 28 459]
[19] Zhang Y J 2007 Optics Communications 274 37
[20] Sheppard C J R, Campos J, Escalera J C, Ledesma S 2008 Optics Communications 281 3623
[21] Delori F C, Pflibsen K P 1989 Applied Optics 28 1061
[22] Tian Y 2008 Ph. D. Dissertation (Chengdu: Institute of Optics and Electronics, Chinese Academy of Science)(in Chinese) [田 雨 2008 博士学位论文 (成都: 中国科学院光电技术研究所)]
[23] Li H, Lu J, Shi G H, Zhang Y D 2010 Biomedical Optics Express 1 31
[24] Zhang H T, Gong M L, Zhao D Z, Yan P, Cui R Z, Jia W P 2001 Acta Phys. Sin. 50 1486 (in Chinese)[张海涛、巩马理、赵达尊、闫 平、崔瑞祯、贾维溥 2001 50 1486]
[25] Liu X M, Liu L R, Bai L H 2006 Chin. Phys. 15 708
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[1] Elsner A E, Zhou Q, Beck F 2000 Opt. Express 7 95
[2] Rawlinson A A , Cucevic V, Nugent K A, Brooks A M V, Klein A G 2000 J. Opt. Soc. Am. 17 477
[3] Fallon T J, Chowiencyzk P, Kohner E M Br 1986 J. Ophthalmol. 70 43
[4] Webb R H, Hughes G W, Delori F C 1987 Apply Optics 26 1492
[5] Liang J, Williams D R, Miller D 1997 J. Opt. Soc. Am. A 14 2884
[6] Roorda A, Romero-Borja F, Donnelly W J, Queener H, Hebert T J, Campbell M C W 2002 Opt. Express 10 405
[7] Zhang Y D, Ling N, Rao X J, Li X Y, Wang W, Ma X A, Jiang W H 2002 Proceeding of the 3rd International Workshop on Adaptive Optics for Industry and Medicine Ed. S. R. Restaino & S. W. Teare 97
[8] Ling N, Zhang Y D, Rao X J, Li X Y, Wang C, Hu Y Y, Jiang W H 2002 Proc. of SPIE 4825 99
[9] Ling N, Zhang Y D, Rao X J, Wang C, Hu Y Y, Jiang W H, Jiang C H 2004 Proc. of SPIE 5639 37
[10] Ling N ,Zhang Y D, Rao X J, Wang C, Hu Y Y, Jiang Y Y 2005 Chinese Optics Letters 3 225
[11] Lu J, Zhang Y D, Rao X J, Shi G H, Yang H S, Wang C 2007 Proc. of SPIE 6624 662420
[12] Lu J, Li H, Wei L, Shi G H, Zhang Y D 2009 Proc. of SPIE 7519 75191l
[13] Shi G H,Dai Y,Wang L,Ding Z H,Rao X J,Zhang Y D 2008 Chinese Optics Letters 6 424
[14] 激光产品的安全.GB 7247.1-2001 idt IEC 60825-1: 1993
[15] Gu M, Tannous T, Sheppard J R 1996 Optics Letters 21 312
[16] Sieracki C K, Hansen E W 1994 Proc. of SPIE 2148 120
[17] Sheppard C J R 1995 Optik 99 32
[18] Deng X Q, Wang G Y, Xu Z Z 2001 Chinese Journal of Lasers 28 459(in Chinese) [邓小强、王桂英、徐至展 2001 中国激光 28 459]
[19] Zhang Y J 2007 Optics Communications 274 37
[20] Sheppard C J R, Campos J, Escalera J C, Ledesma S 2008 Optics Communications 281 3623
[21] Delori F C, Pflibsen K P 1989 Applied Optics 28 1061
[22] Tian Y 2008 Ph. D. Dissertation (Chengdu: Institute of Optics and Electronics, Chinese Academy of Science)(in Chinese) [田 雨 2008 博士学位论文 (成都: 中国科学院光电技术研究所)]
[23] Li H, Lu J, Shi G H, Zhang Y D 2010 Biomedical Optics Express 1 31
[24] Zhang H T, Gong M L, Zhao D Z, Yan P, Cui R Z, Jia W P 2001 Acta Phys. Sin. 50 1486 (in Chinese)[张海涛、巩马理、赵达尊、闫 平、崔瑞祯、贾维溥 2001 50 1486]
[25] Liu X M, Liu L R, Bai L H 2006 Chin. Phys. 15 708
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