X射线光栅微分相衬成像视场分析

杜杨; 刘鑫; 雷耀虎; 黄建衡; 赵志刚; 林丹樱; 郭金川; 李冀; 牛憨笨

doi:10.7498/aps.65.058701

摘要

X射线光栅微分相衬成像对由轻元素构成的物质的内部探测具有传统吸收成像无法比拟的优势, 尤其在癌症的早期诊断和轻元素材料及器件的无损检测等领域应用潜力巨大. 大视场成像是影响该技术从实验室走向实际应用的重要因素. 针对大视场成像的客观需求, 基于菲涅耳衍射原理和光栅结构特征, 建立了量化物理模型用于分析影响成像视场的因素, 提出了实现大成像视场的有效途径, 为未来大视场光栅微分相衬成像方法的设计和应用提供理论依据.

关键词:

Abstract

Grating-based X-ray differential phase contrast imaging provides excellent image contrast for low-Z objects that cannot be acquired by conventional X-ray imaging, which has great potential applications in the early diagnosis of cancer and non-destructive detections of low-Z materials and devices. Large field of view imaging is a crucial factor for this technology from the laboratory to practical application. For the objective need of large field of view, on the basis of the Fresnel diffraction theory and the structure characteristics of gratings, we establish a quantitative physical model to analyze the factors that affect the imaging field of view and give a feasible way for large imaging field of view. This work provides a theoretical basis for the large field of view grating-based X-ray differential phase contrast imaging in the future.

Keywords:

X-ray imaging /
X-ray differential phase contrast imaging /
field of view

作者及机构信息

1.
深圳大学光电工程学院, 光电子器件与系统(教育部、广东省)重点实验室, 深圳 518060

通信作者: 李冀, liji@szu.edu.cn

基金项目: 国家自然科学基金 (批准号: 11404221, 11074172)、中国博士后面上基金(批准号: 2014M562204)、中国博士后科学基金特别资助(批准号: 2015T80914)、深圳市科创委基础研究项目基金(批准号: JCYJ20150525092941019)、国家自然科学基金科学仪器基础研究专款(批准号: 61227802)和国家重点基础研究项目特别基金(批准号: 2012CB825802)资助的课题.

Authors and contacts

1.
Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China

Corresponding author: Li Ji, liji@szu.edu.cn

Funds: Project supported by the National Natural Science Foundation of China (Grant Nos. 11404221, 11074172), the China Postdoctoral Science Foundation (Grant No. 2014M562204), the Special Fund for China Postdoctoral Science Foundation (Grant No. 2015T80914), the Science and Technology Innovation Commission of Shenzhen, China (Grant No. JCYJ20150525092941019), the Special Fund for Basic Research on Scientific Instruments of the National Natural Science Foundation of China (Grant No. 61227802), and the National Key Basic Research Special Foundation of China (NKBRSFC) (Grant No. 2012CB825802).

参考文献

[1]	Momose A, Fukuda J 1995 Med. Phys. 22 375
[2]	Bonse U, Hart M 1965 Appl. Phys. Lett. 6 155
[3]	Hosoya S, Ando M 1971 Phys. Rev. Lett. 26 321
[4]	Momose A, Takeda T, Itai Y, Hirano K 1996 Nat. Med. 2 473
[5]	Davis T J, Gao D C, Gureyev T E, Stevenson A W, Wilkins S W 1995 Nat. 373 595
[6]	Chapman D, Thomlinson W, Johnston R E, Washburn D, Pisano E, Gmr N, Zhong Z, Menk R, Arfelli F, Sayers D 1997 Phys. Med. Biol. 42 2015
[7]	Ingal I V, Beliaevskaya E A 1995 J. Phys. D: Appl. Phys. 28 2314
[8]	Wilkins S W, Gureyev T E, Gao D C, Pogany A, Stevenson A W 1996 Nat. Lett. 384 335
[9]	David C, Nöhammer B, Solak H H, Ziegler E 2002 Appl. Phys. Lett. 81 3287
[10]	Momose A, Kawamoto S, Koyama I, Hamaishi Y, Takai K, Suzuki Y 2003 Jpn. J. Appl. Phys. 42 L866
[11]	Pfeiffer F, Weitkamp T, Bunk O, David C 2006 Nat. Phys. 2 258
[12]	Pfeiffer F, Bech M, Bunk O, Kraft P, Eikenberry E F, Brönnimann C, Grnzweig C, David C 2008 Nat. Mat. 7 134
[13]	Du Y, Liu X, Huang J H, Lei Y H, Zhao Z G, Lin D Y, Guo J C, Li J, Niu H B 2015 Opt. Express 19 12712
[14]	Zhu P P, Zhang K, Wang Z L, Liu Y J, Liu X S, Wu Z Y, McDonald S A, Marone F, Stampanoni M 2010 Proc. Natl. Acad. Sci. 107 13576
[15]	Du Y, Lei Y H, Liu X, Guo J C, Niu H B 2013 Acta Phys. Sin. 62 068702 (in Chinese) [杜杨, 雷耀虎, 刘鑫, 郭金川, 牛憨笨 2013 62 068702]
[16]	Kottler C, Pfeiffer F, Bunk O, Grunzweig C, Bruder J, Kaufmann R, Tlustos L, Walt H, Briod I, Weitkamp T, David C 2007 Phys. Status. Solidi. A 204 2728
[17]	Donath T, Pfeiffer F, Bunk O, Grunzweig C, Hempel E, Popescu S, Vock P, David C 2010 Invest. Radiol. 45 445
[18]	Du Y, Liu X, Lei Y H, Guo J C, Niu H B 2011 Opt. Express 19 22669
[19]	Momose A, Yashiro W, Kido K, Kiyohara J, Makifuchi C, Ito T, Nagatsuka S, Honda C, Noda D, Hattori T, Endo T, Nagashima M, Tanaka J 2014 Phil. Trans. R. Soc. A 372 20130023
[20]	Revol V, Kottler C, Kaufmann R, Straumann U, Urban C 2010 Rev. Sci. Instrum. 81 073709
[21]	Modregger P, Pinzer B R, Thring T, Rutishauser S, David C, Stampanoni M 2011 Opt. Express 19 18324
[22]	Huang J H, Du Y, Lei Y H, Liu X, Guo J C, Niu H B 2014 Acta Phys. Sin. 63 168702 (in Chinese) [黄建衡, 杜杨, 雷耀虎, 刘鑫, 郭金川, 牛憨笨 2014 63 168702]
[23]	Noda D, Tsujii H, Takahashi N, Hattori T 2009 J. Electrochem. Soc. 156 H299
[24]	David C, Bruder J, Rohbeck T, Grnzweig C, Kottler C, Diaz A, Bunk O, Pfeiffer F 2007 Microelectron. Eng. 84 1172
[25]	Liu X, Lei Y H, Zhao Z G, Guo J C, Niu H B 2010 Acta Phys. Sin. 59 6927 (in Chinese) [刘鑫, 雷耀虎, 赵志刚, 郭金川, 牛憨笨 2010 59 6927]
[26]	Thuering T, Modregger P, Grund T, Kenntner J, David C, Stampanoni M 2011 Appl. Phys. Lett. 99 041111
[27]	Du Y, Huang J H, Lin D Y, Niu H B 2012 Anal. Bioanal. Chem. 404 793

施引文献

[1]	Momose A, Fukuda J 1995 Med. Phys. 22 375
[2]	Bonse U, Hart M 1965 Appl. Phys. Lett. 6 155
[3]	Hosoya S, Ando M 1971 Phys. Rev. Lett. 26 321
[4]	Momose A, Takeda T, Itai Y, Hirano K 1996 Nat. Med. 2 473
[5]	Davis T J, Gao D C, Gureyev T E, Stevenson A W, Wilkins S W 1995 Nat. 373 595
[6]	Chapman D, Thomlinson W, Johnston R E, Washburn D, Pisano E, Gmr N, Zhong Z, Menk R, Arfelli F, Sayers D 1997 Phys. Med. Biol. 42 2015
[7]	Ingal I V, Beliaevskaya E A 1995 J. Phys. D: Appl. Phys. 28 2314
[8]	Wilkins S W, Gureyev T E, Gao D C, Pogany A, Stevenson A W 1996 Nat. Lett. 384 335
[9]	David C, Nöhammer B, Solak H H, Ziegler E 2002 Appl. Phys. Lett. 81 3287
[10]	Momose A, Kawamoto S, Koyama I, Hamaishi Y, Takai K, Suzuki Y 2003 Jpn. J. Appl. Phys. 42 L866
[11]	Pfeiffer F, Weitkamp T, Bunk O, David C 2006 Nat. Phys. 2 258
[12]	Pfeiffer F, Bech M, Bunk O, Kraft P, Eikenberry E F, Brönnimann C, Grnzweig C, David C 2008 Nat. Mat. 7 134
[13]	Du Y, Liu X, Huang J H, Lei Y H, Zhao Z G, Lin D Y, Guo J C, Li J, Niu H B 2015 Opt. Express 19 12712
[14]	Zhu P P, Zhang K, Wang Z L, Liu Y J, Liu X S, Wu Z Y, McDonald S A, Marone F, Stampanoni M 2010 Proc. Natl. Acad. Sci. 107 13576
[15]	Du Y, Lei Y H, Liu X, Guo J C, Niu H B 2013 Acta Phys. Sin. 62 068702 (in Chinese) [杜杨, 雷耀虎, 刘鑫, 郭金川, 牛憨笨 2013 62 068702]
[16]	Kottler C, Pfeiffer F, Bunk O, Grunzweig C, Bruder J, Kaufmann R, Tlustos L, Walt H, Briod I, Weitkamp T, David C 2007 Phys. Status. Solidi. A 204 2728
[17]	Donath T, Pfeiffer F, Bunk O, Grunzweig C, Hempel E, Popescu S, Vock P, David C 2010 Invest. Radiol. 45 445
[18]	Du Y, Liu X, Lei Y H, Guo J C, Niu H B 2011 Opt. Express 19 22669
[19]	Momose A, Yashiro W, Kido K, Kiyohara J, Makifuchi C, Ito T, Nagatsuka S, Honda C, Noda D, Hattori T, Endo T, Nagashima M, Tanaka J 2014 Phil. Trans. R. Soc. A 372 20130023
[20]	Revol V, Kottler C, Kaufmann R, Straumann U, Urban C 2010 Rev. Sci. Instrum. 81 073709
[21]	Modregger P, Pinzer B R, Thring T, Rutishauser S, David C, Stampanoni M 2011 Opt. Express 19 18324
[22]	Huang J H, Du Y, Lei Y H, Liu X, Guo J C, Niu H B 2014 Acta Phys. Sin. 63 168702 (in Chinese) [黄建衡, 杜杨, 雷耀虎, 刘鑫, 郭金川, 牛憨笨 2014 63 168702]
[23]	Noda D, Tsujii H, Takahashi N, Hattori T 2009 J. Electrochem. Soc. 156 H299
[24]	David C, Bruder J, Rohbeck T, Grnzweig C, Kottler C, Diaz A, Bunk O, Pfeiffer F 2007 Microelectron. Eng. 84 1172
[25]	Liu X, Lei Y H, Zhao Z G, Guo J C, Niu H B 2010 Acta Phys. Sin. 59 6927 (in Chinese) [刘鑫, 雷耀虎, 赵志刚, 郭金川, 牛憨笨 2010 59 6927]
[26]	Thuering T, Modregger P, Grund T, Kenntner J, David C, Stampanoni M 2011 Appl. Phys. Lett. 99 041111
[27]	Du Y, Huang J H, Lin D Y, Niu H B 2012 Anal. Bioanal. Chem. 404 793

[1]	廖可梁, 何其利, 宋杨, 李荣刚, 宋茂华, 李盼云, 赵海峰, 刘鹏, 朱佩平. 基于实验室光源的透射X射线纳米分辨显微镜研制. , 2024, 73(17): 178701. doi: 10.7498/aps.73.20240727
[2]	陈子涵, 宋梦齐, 陈恒, 王志立. 双三角形相位光栅X射线干涉仪的条纹可见度. , 2023, 72(14): 148701. doi: 10.7498/aps.72.20230461
[3]	周腊珍, 夏文静, 许倩倩, 陈赞, 李坊佐, 刘志国, 孙天希. 一种基于毛细管X光透镜的微型锥束CT扫描仪. , 2022, 71(9): 090701. doi: 10.7498/aps.71.20212195
[4]	鞠晓璐, 李可, 余福成, 许明伟, 邓彪, 李宾, 肖体乔. 电解池电化学反应过程的运动衬度X射线成像. , 2022, 71(14): 144101. doi: 10.7498/aps.71.20220339
[5]	汤明玉, 武梦婷, 臧瑞环, 荣腾达, 杜艳丽, 马凤英, 段智勇, 弓巧侠. 菲涅耳非相干数字全息大视场研究. , 2019, 68(10): 104204. doi: 10.7498/aps.68.20182216
[6]	戚俊成, 刘宾, 陈荣昌, 夏正德, 肖体乔. X射线光场成像技术研究. , 2019, 68(2): 024202. doi: 10.7498/aps.68.20181555
[7]	戚俊成, 陈荣昌, 刘宾, 陈平, 杜国浩, 肖体乔. 基于迭代重建算法的X射线光栅相位CT成像. , 2017, 66(5): 054202. doi: 10.7498/aps.66.054202
[8]	荣锋, 谢艳娜, 邰雪凤, 耿磊. 双能X射线光栅相衬成像的研究. , 2017, 66(1): 018701. doi: 10.7498/aps.66.018701
[9]	刘鑫, 易明皓, 郭金川. 线焦斑X射线源成像. , 2016, 65(21): 219501. doi: 10.7498/aps.65.219501
[10]	黄建衡, 杜杨, 雷耀虎, 刘鑫, 郭金川, 牛憨笨. 硬X射线微分相衬成像的噪声特性分析. , 2014, 63(16): 168702. doi: 10.7498/aps.63.168702
[11]	杜杨, 雷耀虎, 刘鑫, 郭金川, 牛憨笨. 硬X射线光栅微分干涉相衬成像两步相移算法的理论与实验研究. , 2013, 62(6): 068702. doi: 10.7498/aps.62.068702
[12]	陈晓虎, 王晓方, 张巍巍, 汪文慧. 相位型波带板应用于大尺度X射线源成像的分析与模拟. , 2013, 62(1): 015208. doi: 10.7498/aps.62.015208
[13]	穆廷魁, 张淳民, 任文艺, 张霖, 祝宝辉. 偏振干涉成像光谱仪的视场展宽设计与分析. , 2011, 60(7): 070704. doi: 10.7498/aps.60.070704
[14]	程冠晓, 胡超. X射线相衬成像光子筛. , 2011, 60(8): 080703. doi: 10.7498/aps.60.080703
[15]	王晓方, 王晶宇. 菲涅耳波带板应用于聚变靶的高分辨X射线成像分析. , 2011, 60(2): 025212. doi: 10.7498/aps.60.025212
[16]	吴海英, 张淳民, 赵葆常. 基于组合Wollaston棱镜成像光谱仪的视场扩大原理分析. , 2009, 58(2): 930-935. doi: 10.7498/aps.58.930
[17]	陈博, 朱佩平, 刘宜晋, 王寯越, 袁清习, 黄万霞, 明海, 吴自玉. X射线光栅相位成像的理论和方法. , 2008, 57(3): 1576-1581. doi: 10.7498/aps.57.1576
[18]	刘丽想, 杜国浩, 胡雯, 骆玉宇, 谢红兰, 陈敏, 肖体乔. 利用定量相衬成像消除X射线同轴轮廓成像中散射的影响. , 2006, 55(12): 6387-6394. doi: 10.7498/aps.55.6387
[19]	于斌, 彭翔, 田劲东, 牛憨笨. 硬x射线同轴相衬成像的相位恢复. , 2005, 54(5): 2034-2037. doi: 10.7498/aps.54.2034
[20]	陈　敏, 肖体乔, 骆玉宇, 刘丽想, 魏　逊, 杜国浩, 徐洪杰. 微聚焦管硬x射线位相衬度成像. , 2004, 53(9): 2953-2957. doi: 10.7498/aps.53.2953

计量

文章访问数: 6254
PDF下载量: 201
被引次数: 0

姓名
邮箱
手机号码
标题
留言内容
验证码

搜索

留言板