硬X射线微分相衬成像的噪声特性分析

黄建衡; 杜杨; 雷耀虎; 刘鑫; 郭金川; 牛憨笨

doi:10.7498/aps.63.168702

摘要

量子噪声引起光强随机波动是影响X射线相衬图像质量的一个重要因素. 提出了一种针对硬X 射线微分相衬成像噪声特性的分析方法，通过数值模拟获得了量子噪声对成像结果的作用规律. 模拟结果表明，折射像和散射像的噪声均方差与叠栅条纹对比度成反比关系，叠栅条纹对比度越大，统计所得的均方差值越小. 在保证X射线探测效率的前提下，提高叠栅条纹对比度将有利于获得高质量的相衬图像，并为有效减少X射线曝光剂量提供条件.

关键词:

Abstract

Quantum noise is an important factor influencing the quality of the images obtained by X-ray phase contrast imaging because it induces a random fluctuation on the intensity. In this paper, a method is reported to analyze the noise characteristics of hard X-ray differential phase contrast imaging, and the relationship between the quantum noise and images is determined by numerical simulation. The results show that the mean square deviations of the refractive and scattering images are inversely proportional to the visibility of moir fringe. That is to say, the higher visibility of moir fringe leads to the lower mean square deviations of the refractive and scattering images. Therefore, in the case of ensuring an enough X-ray detection efficiency, the improvement in the visibility of moir fringe will be beneficial to obtaining high-quality phase contrast images and the effective reduction of X-ray exposure dose.

Keywords:

作者及机构信息

1.
深圳大学光电工程学院, 光电子器件与系统教育部重点实验室, 广东省光电子器件与系统重点实验室, 深圳 518060

基金项目: 国家重大科学仪器设备开发专项基金（批准号：61227802）、国家自然科学基金（批准号：11074172，61101175）和深圳市新产业发展专项基金（批准号：CXB201005240011A，JC201005280502A）资助的课题.

Authors and contacts

1.
Key Laboratory of Optoelectronic Devices and Systems of Guangdong Province, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China

Funds: Project supported by the Special Foundation of State Major Scientific Instrument and Equipment Development of China (Grant No. 61227802), the National Natural Science Foundation of China (Grant Nos. 11074172, 61101175), and the Special Foundation for New Industry Development of Shenzhen, China (Grant Nos. CXB201005240011A, JC201005280502A).

参考文献

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[2]	Henke B L, Gullikson E M, Davis J C 1993 At. Data Nucl. Data Tables 54 181
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[6]	Zhou S A, Brahme A 2008 Phys. Med. 24 129
[7]	Keyrilainen J, Bravin A, Fernandez M, Tenhunen M, Virkkunen P, Suortti P 2010 Acta Radiol. 51 866
[8]	Pfeiffer F, Weitkamp T, Bunk O, David C 2006 Nat. Phys. 2 258
[9]	Pfeiffer F, Bech M, Bunk O, Kraft P, Eikenberry F E, Bronnimann C, Grunzweig C, David C 2008 Nat. Mater. 7 134
[10]	Du Y, Liu X, Lei Y H, Guo J C, Niu H B 2011 Opt. Express 19 22669
[11]	Liu X, Guo J C 2011 Acta Photon. Sin. 40 242 (in Chinese) [刘鑫, 郭金川 2011 光子学报 40 242]
[12]	Guo J C, Zhou B, Liu X, Ren X K, Niu H B 2011 J. Shenzhen Univ. (Sci. Eng. Ed.) 28 311
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[14]	Revol V, Kottler C, Kaufmann R, Straumann U, Urban C 2010 Rev. Sci. Instrum. 81 073709
[15]	Engel K J, Geller D, Kohler T, Martens G, Schusser S, Vogtmeier G, Rossl E 2011 Nucl. Instrum. Meth. A 648 202
[16]	David C, Nohammer B, Solak H H 2002 Appl. Phys. Lett. 81 3287
[17]	Momose A, Kawamoto S, Koyama I, Hamaishi Y, Takai K, Suzuki Y 2003 Jpn. J. Appl. Phys. 42 L886
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[19]	An Y Y, Zeng X D 2004 Principle of Photoelectric Detection (Xi'an: Xidian University Press) pp238-239 (in Chinese) [安毓英, 曾晓东 2004 光电探测原理 (西安: 西安电子科技大学出版社) 第238–239页]
[20]	Sun R H, Yi H Y, Liu Q S, He Z S 2000 Probability Theory and Mathematical Statistics (Chongqing: Chongqing University Press) pp107-110 (in Chinese) [孙荣恒, 伊亨云, 刘琼荪, 何中市 2000 概率论和数理统计 (重庆: 重庆大学出版社) 第107–110页]
[21]	Weitkamp T, Diaz A, David C, Pfeiffer F, Stampanoni M, Cloetens P, Ziegler E 2005 Opt. Express 13 6296
[22]	Yang Q, Liu X, Guo J C, Lei Y H, Huang J H, Niu H B 2012 Acta Phys. Sin. 61 160702 (in Chinese) [杨强, 刘鑫, 郭金川, 雷耀虎, 黄建衡, 牛憨笨 2012 61 160702]
[23]	Lei Y H, Liu X, Guo J C, Zhao Z G, Niu H B 2011 Chin. Phys. B 20 042901

施引文献

[1]	Fitzgerald R 2000 Phys. Today 53 23
[2]	Henke B L, Gullikson E M, Davis J C 1993 At. Data Nucl. Data Tables 54 181
[3]	Chen B, Zhu P P, Liu Y J, Wang J Y, Yuan Q X, Huang W X, Ming H, Wu Z Y 2008 Acta Phys. Sin. 57 1576 (in Chinese) [陈博, 朱佩平, 刘宜晋, 王寯越, 袁清习, 黄万霞, 明海, 吴自玉 2008 57 1576]
[4]	Du Y, Lei Y H, Liu X, Guo J C, Niu H B 2013 Acta Phys. Sin. 62 068702 (in Chinese) [杜杨, 雷耀虎, 刘鑫, 郭金川, 牛憨笨 2013 62 068702]
[5]	Lewis R A 2004 Phys. Med. Biol. 49 3573
[6]	Zhou S A, Brahme A 2008 Phys. Med. 24 129
[7]	Keyrilainen J, Bravin A, Fernandez M, Tenhunen M, Virkkunen P, Suortti P 2010 Acta Radiol. 51 866
[8]	Pfeiffer F, Weitkamp T, Bunk O, David C 2006 Nat. Phys. 2 258
[9]	Pfeiffer F, Bech M, Bunk O, Kraft P, Eikenberry F E, Bronnimann C, Grunzweig C, David C 2008 Nat. Mater. 7 134
[10]	Du Y, Liu X, Lei Y H, Guo J C, Niu H B 2011 Opt. Express 19 22669
[11]	Liu X, Guo J C 2011 Acta Photon. Sin. 40 242 (in Chinese) [刘鑫, 郭金川 2011 光子学报 40 242]
[12]	Guo J C, Zhou B, Liu X, Ren X K, Niu H B 2011 J. Shenzhen Univ. (Sci. Eng. Ed.) 28 311
[13]	Momose A, Yashiro W, Takeda Y 2008 Jpn. J. Appl. Phys. 47 8077
[14]	Revol V, Kottler C, Kaufmann R, Straumann U, Urban C 2010 Rev. Sci. Instrum. 81 073709
[15]	Engel K J, Geller D, Kohler T, Martens G, Schusser S, Vogtmeier G, Rossl E 2011 Nucl. Instrum. Meth. A 648 202
[16]	David C, Nohammer B, Solak H H 2002 Appl. Phys. Lett. 81 3287
[17]	Momose A, Kawamoto S, Koyama I, Hamaishi Y, Takai K, Suzuki Y 2003 Jpn. J. Appl. Phys. 42 L886
[18]	Goodman J W (translated by Qin K C, Liu P S, Chen J B, Cao Q Z) 2006 Introduction to Fourier Optics (Beijing: Publishing House of Electronics Industry) pp78-82 (in Chinese) [古德曼 J W著 (秦克诚, 刘培森, 陈家璧, 曹其智译) 2006 傅里叶光学导论 (北京: 电子工业出版社) 第78–82页]
[19]	An Y Y, Zeng X D 2004 Principle of Photoelectric Detection (Xi'an: Xidian University Press) pp238-239 (in Chinese) [安毓英, 曾晓东 2004 光电探测原理 (西安: 西安电子科技大学出版社) 第238–239页]
[20]	Sun R H, Yi H Y, Liu Q S, He Z S 2000 Probability Theory and Mathematical Statistics (Chongqing: Chongqing University Press) pp107-110 (in Chinese) [孙荣恒, 伊亨云, 刘琼荪, 何中市 2000 概率论和数理统计 (重庆: 重庆大学出版社) 第107–110页]
[21]	Weitkamp T, Diaz A, David C, Pfeiffer F, Stampanoni M, Cloetens P, Ziegler E 2005 Opt. Express 13 6296
[22]	Yang Q, Liu X, Guo J C, Lei Y H, Huang J H, Niu H B 2012 Acta Phys. Sin. 61 160702 (in Chinese) [杨强, 刘鑫, 郭金川, 雷耀虎, 黄建衡, 牛憨笨 2012 61 160702]
[23]	Lei Y H, Liu X, Guo J C, Zhao Z G, Niu H B 2011 Chin. Phys. B 20 042901

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