The fluorescence blinking characteristics of the single CdSe/ZnS core/shell quantum dots (QDs) absorbed on the cover glass surface, indium-tin oxide (ITO) nanoparticles, and polymethyl methacrylate (PMMA) film surface are measured by a laser scanning confocal fluorescence microscopy. It is found that all the distributions of bright state duration time of QDs on the three different interfaces can be described by a truncated power law P(t)∝ t-αexp(-t/μ). The statistical on-time durations of single QDs absorbed on the ITO nanoparticles is shorter than on the glass. In addition, the on-time duration with single QDs absorbed on the PMMA is longer than on the others. These differences can be attributed to the diverse interfacial electron transfers between QD and different materials.